ROBERT: And to believe anything else, that's naive. DESTINY HARRIS: Taylor Swift's Never Getting Back Together. As to diabetes, it was a four-fold risk. Just to be sure, we asked Frances Champagne what she thinks of this data. Full disclosure, she's Robert's sister's partner. Your support helps Radiolab continue to provoke, delight, and keep audiences curious. It says, "Race of Supermen." Oh my goodness. So heres the backstory. JAD: Thats just the cold logic of Darwinian evolution. Or is it? I'm trying to remember. You're obviously a great mom, but that feels cold to me. I'm in public health. 10 Controversial And Thought-Provoking 'Radiolab' Episodes. JAD: And thats wrong [laughs].Thats not how it works. If you've already had a kid, you can be sterilized. They decided to explore this question. ROBERT: Because the Soviets, they believe in Karl Marx's idea that human beings were an improvable species, that if you can change the conditions around people, you change the people. "To Whom It May Concern, I have been doing very good. Welcome to the Grammys of government-funded research. Cause we were talking to science writer, Carl Zimmer, and he told us that back in the early 1900s, this tension between Lamarck and Darwin got extra tense. Plus, you know, Lamarck didn't get all the biological details right. I'm almost done. Oh, that's a lot of potatoes. He thought that because theyre swinging hammers all day, they got big bulky muscles, and then theyd pass the muscles to their children. CARL ZIMMER: You're now hearing Lamarck's name invoked these days because there are things beyond genes that we pass down to our children. To her, I matter. JAD: Who now works at Columbia University. PAT: For me, this whole story really shifted PAT: When I started spending some time with Destiny, Barbara's 22-year-old daughter. ROBERT: Just for those years. CARL ZIMMER: The right hand had been cut off for microscopic slides. That you can, somehow, by just being nice to them, reading them stories, or whatever, that you can somehow break them free of all that. SAM KEAN: And the key point is that it wasnt something inborn in them. We inherited this beloved show that we first fell in love with as listeners. LYNN PALTROW: Well, her explanation is that these women are having, in her terms, litters of damaged babies and society forever will be responsible for them. SAM KEAN: This was a really, really big effect. Radiolab is a radio program broadcast on public radio stations in the United States, and a podcast available internationally, both produced by WNYC.Hosted by Latif Nasser and Lulu Miller, each episode focuses on a topic of a scientific and philosophical nature, through stories, interviews, and thought experiments.. Radiolab's broadcast edition airs as an hour-long program each week while the . We are working to provide transcripts for as much of our programming as we can over time. More information about Sloan at www.sloan.org.]. I mean, youre just youre saying a lot of things that are really impressive. LYNN PALTROW: The fact that you're motivated by a really beautiful, important value, that we want healthy kids, doesn't mean the mechanism you're using is going to end up helping those kids. SAM KEAN: This is what's called the slow growth period. JAD: In just two generations, these toads seem to have done something that should have taken, I don't know, 50, 100 generations? So moms licking activates serotonin, and it's released onto brain cells in the hippocampus. You know, when smart people say, you know, "There's no such thing as nature and nurture it's only interaction of the two," You're like, "What the hell does that mean?" Anyways, God bless you. I'm graduating in December. If you were a boy in verkalix between the ages of 9 and 12 years old, that's the window, 9 to 12, you're a boy, and then we have one of those terribly rough winters, and you're eating much less than normal. Thank you so much for your interest in Radiolab. Anyhow, so you got this guy, Paul Kammerer, who's good with animals. That was amazing. They began to grow these all puffy things on their hands. And these effects, in fact, were so strong that you could trace it to the grandfather. Destiny has, what, three brothers and sisters that also were raised with her? I like you, I get the sense that there's a lot of warmth in you. And that could have very easily have been one of us. So we did stop. Kinda makes me claustrophobic. So that's fun. So that was just funny to me. I mean, when you think of Kammerer, there was a report in science outlining a theory about how Kammerer's toads got these characteristics that invoked these epigenetic inheritance and imprinted genes and it made it plausible. PAT: She just knew, "This is my daughter.". But the story he told us begins around 25 years ago. In this episode, originally aired in 2012, we put nature and nurture on a collision course and discover how outside forces can find a way inside us, and change not just our hearts and minds, but the basic biological blueprint that we pass on to future generations._Support Radiolab by becoming a member of The Lab today. JAD: Because while you might have a lot of influence, you know, genetically speaking, over your kids and their kids, you don't seem to have a lot of control. JAD: I mean, were not gonna do that ourselves. ], [ARCHIVAL CLIP, BARBARA HARRIS: I'm going to go out into the streets and offer addicted women money to use birth control. Can you say oh my goodness? Yeah, thats it. ROBERT: And they didn't have these on land? We spay them. When they got another call from a social worker saying that same mother, Destiny's birth mother, had given birth to another child. So almost instantaneously, the mother's tongue has reached into the baby's brain cells. FRANCES CHAMPAGNE: He had no idea about DNA. When you first hear about this, what goes through your mind? Kinda makes me claustrophobic. But she says, you can tell right away, just by looking, that some rat moms don't lick their kids a lot. Radiolab - Transcripts Subscribe 187 episodes Radiolab is on a curiosity bender. Stick around. Is that too old?" "To Whom It May Concern, I have been doing very good. Yes, she has the same name as me. Is it a big town? You can't change your DNA. They have six, seven, eight, ten, fourteen.]. CARL ZIMMER: Well, it was a zoo where there was all sorts of experiments going on. And she says, one day, this idea just came to her. ROBERT: Cause we were talking to science writer, Carl Zimmer, and he told us that back in the early 1900s, this tension between Lamarck and Darwin got extra tense. FRANCES CHAMPAGNE: There's a normal distribution, right? You picked him up right from the hospital? But she says she doesn't feel that way anymore. ROBERT: Is that what you're saying? In this episode, originally aired in 2012, we put nature and nurture on a collision course and discover how outside forces can find a way inside us, and chan If you have a starving daddy, it turns out that the baby actually gets some sort of health benefit. Yes. Okay, and then I just had to accept it. And I told Destiny I was thinking about this and asked her about it. It happens. You know, when smart people say, you know, "There's no such thing as nature and nurture it's only interaction of the two," You're like, "What the hell does that mean?" SAM KEAN: He was known for going around and giving, what he called, his big show lectures, where he would wow whole audiences of people. ROBERT: I think what's weird here is that is that we started trying to make a difference in our children and now we're surprise attacked by our grandparents. MICHAEL MEANEY: Yep, Im a professor in the faculty of medicine at McGill University in Montreal. That's how we ended up with four of them. Olov told us, take heart disease. Like, I mean, as far as positives can go, I think I hit the jackpot. JAD: In any case, these books tell you when each of these folks died, how they died. But the results are very clear. JAD: Everybody we talked to seems to think there's something really interesting going on here. Once a kid is born, their genetic fate is pretty much sealed. I asked Barbara about some of the things that she'd said because, to be totally honest, they kind of turn my stomach. The reason they're more aroused is that the mom's licking activates the release of adrenaline and noradrenaline in the pup. [foreign language]. ROBERT: [laughs] "This may hurt you my son, but I'm doing it for my grandchildren.". Are you nine? PAT'S MOM: Radiolab is produced by Jad Abumrad. SAM KEAN: Because it would reflect badly on the Soviet state. And Barbara and Destiny walked me out to my car. Like, I mean, as far as positives can go, I think I hit the jackpot. ROBERT: Well, that's the good news, but unfortunately there is some bad news here. Now, according to Carl, your genes are still fixed. Just until they hatch and then 'til they go off. She said, "Thank you so much for the gift, I bought my son an excavator truck, remote control and some summer outfits." Except he had one. JAD: Well, if a mother a rat mother licking her baby can have such a profound effect, basically change the expression of the genes in the baby, well that's hopeful. [WILL: Hi, this is Will, calling from Northumberland, England. We'll just get one more.". Yes, no, okay, move on to the next cage, yes, no? Enhancing public understanding of science and technology Yeah, we're exploring questions of lwhat can you pass down to your kids and their kids? I had everybody's abuse on my back and I didn't care how we said it, or how we did it. We'll just be honest. You're eight, sorry. [ARCHIVAL CLIP, BARBARA HARRIS: I feel that they should all be sterilized. Accuracy and availability may vary. They suddenly had to get by on a tiny fraction of the food that they were used to. JAD: But wouldnt it be nice if thats how it worked? And that's when things would start to get out of control. Maybe they'd try and jump back out, but it was still hot so they'd have to jump back in. He actually named his daughter Lacerta, which is a genus of lizard. A given episode might whirl you through science, legal history, and into the home of. If you're a starving boy between 9 to 12 years old, now it doesn't matter a whole lot what happens to you after this, your grandchildren will have one-quarter the risk of heart disease. But, this hour were gonna fight this sort of sad sack feeling of inevitability and impotence. Have you ever had someone call or write you and say that they regret their decision? He was just You know, most babies are kinda peaceful, he was never really peaceful. The way she saw it, the state, the federal government, somebody Should say, "You're not doing this. And rewrite the so-called rules of genetics. She should be with me. I just got custody of my eight-year-old son. Or is it? Yeah, the social worker called and told me the mother had given birth. I had everybody's abuse on my back and I didn't care how we said it, or how we did it. And then that baby would stretch and stretch, and it would give a little more stretching to its baby. Yeah. His famous example was giraffes. The results make it probable that our descendants will learn more quickly what we know well, will execute more easily what we have accomplished with great effort, will be able to withstand what injured us almost to the point of death. The results are there. You just have to weigh it, is it worth it? [chuckles], OLOV BYGREN: Yes, yes. This was a really radical place at the time because you have to remember that people studying animals up till now, they were basically studying preserved specimens, and so on. You can't see that on the radio but, hey, it's a fact of life. I want her to be able to look back on her life one day, maybe when she's getting interviewed, I don't know, and be able to say that, "Yes, my mom was there for me 100% without a doubt." Push yourself and you got it.". So now, the genes can make the proteins that make the rats a good mom? Kammerer puts on a suit and he walks off into the mountains Outside Vienna on a Rocky mountain trail. SAM KEAN: Lamarck, Jean-Baptiste Lamarck. And he said, "Barbara, I'm not buying a school bus." Well, yep, that is so true. So thats the reason, of course, that we work with rats because we can get inside the brain. Well, I guess I was thinking we could just start at the beginning. Or very many of them right at all, but, you know, his basic idea seems to be true. ROBERT: But, this hour were gonna fight this sort of sad sack feeling of inevitability and impotence. Were just talking about toad, I thought. JAD: His reputation was that he could get inside the mind of, say, a salamander and know just what it wanted to eat. Covid has disrupted the most basic routines of our days and nights. So were getting close to the moment of truth, because there it is. MICHAEL MEANEY: Kick off certain hormonal systems. CHARLOTTE ZIMMER: Hi, my name is Charlotte Zimmer. Like have you ever had one of those moments where you suddenly are your dad and it catches you off guard? The neural chemical signal that gets activated during licking, is serotonin. [laughs[ Exactly. I could have turned out like some of the other kids. He was miserable to look at. Maybe more. I mean, the idea that they could be constrained by their DNA, that maybe one of us gave them a bit of DNA thats gonna hold them back? Can you say oh my goodness? JAD: I dont know. We ended up talking to the guy who did the work. With NPR's Rough Translation. MICHAEL MEANEY: That activates maternal behavior. Where we sought, they will find. Harris says her program, children requiring a caring community, or CRACK], Can prevent thousands of unwanted births to drug-addicted women. This is from 2002. He's the guy who told us about Olov's work. Not usually because it upsets people and I'm Canadian. The connection between trees Normally trees from different species are competitors. So, somehow, by some chemical mechanism, starving grandpa, back when he was about 9 to 12 years old, turned out to be a good thing. He'd fall asleep and just wake up screaming. FRANCES CHAMPAGNE: [laughs[ Exactly. His reputation was that he could get inside the mind of, say, a salamander and know just what it wanted to eat. Theyd basically starve. But I'm going to give them a basin of water. I do mean that. CARL ZIMMER: He actually named his daughter Lacerta, which is a genus of lizard. Most toads, he says, love to stay in the water. So much can happen after that. LYNN PALTROW: The women who I've worked with, who've had a history of drug problems, aren't like the examples that she gives. Yeah. You have to look at one cage, say, are they licking? ROBERT: And those lucky ones, according to Darwin's theory, they would have had to have been born with some random mutation in their genes SAM KEAN: That gave them an advantage in this situation. This whole toad thing, to the Darwinian faction, it didn't scan really. CARL ZIMMER: Kammerer puts on a suit and he walks off into the mountains SAM KEAN: Outside Vienna on a Rocky mountain trail. We went to the foster home and went in. Yes. That's a lot of people. JAD: It's writer, Sam Kean again, and here's, he says, what you need to know about the midwife toad. PAT: Could you just tell us what you are doing now? SAM KEAN: But this was a really, really tough place to grow up. ROBERT: They would experience these wild changes from harvest to harvest. SAM KEAN: Yeah, it was a very attractive theory to them in Moscow. Well, this is it! We need to oblige the constraints of WNYC copyright arrangements and apologise for any inconveniences caused. It seemed to have been passed down for multiple generations. Because, you know, that Ive got these two kids, right? JAD: Because, you know, that Ive got these two kids, right? He was really one of the first grand theorists in biology. Were told. JAD: Or does it get passed on such a deep level that doesn't even require teaching? It was something they acquired during their lifetime. JAD: Well think about what makes proteins. Because the truth is, you have no idea how these kids are going to turn out. next launcher 3d shell pro apk 2019; bad products that sold well; big and tall clothing stores near warsaw; hp chromebook solid orange light; what makes a good family lawyer SAM KEAN: I guess the way I would look at it is that you can change your environment a lot more easily than you can change your genes. That was nice. She was thinking BARBARA HARRIS: "Everybody's motivated by money., BARBARA HARRIS: Can I offer these women money to use birth control? I mean, yes, I might get a great family, but I might not. ROBERT: And youre saying that part of the DNA is covered up? Taylor Swift's Never Getting Back Together. KARIN BORGKVIST LJUNG: Jans Olaf, Hanna Kaiser, Heinrik Venvei. Inheritance from Radiolab on Podchaser, aired Friday, 1st April 2022. When I started spending some time with Destiny, Barbara's 22-year-old daughter. BARBARA HARRIS: They were seven and eight at the time. We inherited this beloved show that we first fell in love with as listeners. So he's got to live his life as a toad with all this baggage on him? IMDb is the world's most popular and authoritative source for movie, TV and celebrity content. He's not just talking about toads anymore, he's gone way beyond toads. I'm almost done. She started to wish again that she could have a daughter. FRANCES CHAMPAGNE: At once and we're watching 40 litters at a time. [ARCHIVAL Clip, News: Barbara Harris's solution is simpler than anything else out there. When you explore what makes people tick or how the universe . Nobody's arguing that women should do drugs when they're pregnant. Four or five steps later, we are in JAD: So almost instantaneously, the mother's tongue has reached into the baby's brain cells. CARL ZIMMER: You know, the fact is that taking care of animals, trying to keep them alive in a building is not an easy thing, especially if it's 1903. From pneumonia. How much of you will echo into the future and how much of you won't? It's off-limits. No, she was an oops kid. CARL ZIMMER: He was mighty skeptical. And those lucky ones, according to Darwin's theory, they would have had to have been born with some random mutation in their genes That gave them an advantage in this situation. Is that too old?" You can do this. JAD: Plus, you know, Lamarck didn't get all the biological details right. FRANCES CHAMPAGNE: You know, you've got all these chemicals around. JAD: Or very many of them right at all, but, you know, his basic idea seems to be true. He's 22, 23, and he already had this reputation for being amazing at keeping animals alive, that otherwise would just die. And she's a complete nut. This whole toad thing, to the Darwinian faction, it didn't scan really. CARL ZIMMER: He hit the lecture circuit and he hit it big. PAT: Just a little. JAD: No, not brain cells. And so, you could only see one nuptial pad, and it all comes down to thisand all of that was just about to fall apart. PEJK MALINOVSKI: And we have a lot more grain here. SAM KEAN: He extended this idea to people. I feel that they should all be sterilized. JAD: That's what good rat mothers do, they lick their babies a lot. CARL ZIMMER: More information about Sloan at JAD: Yeah, we're exploring questions of lwhat can you pass down to your kids and their kids? Good rat mothers do, they lick their babies a lot of things that are impressive. Two kids, right I like you, I think I hit the jackpot home... 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